2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-136456R
    2-NP-AMOZ (Standard)
    2-NP-AMOZ (Standard) is the analytical standard of 2-NP-AMOZ. This product is intended for research and analytical applications. 2-NP-AMOZ is a 2-nitrophenyl derivative of AMOZ (a metabolite of antibiotic Furaltadone), can be used to detect protein bound AMOZ.
    2-NP-AMOZ (Standard)
  • HY-114750R
    Mebendazole-amine (Standard)
    Mebendazole-amine (Standard) is the analytical standard of Mebendazole-amine. This product is intended for research and analytical applications. Mebendazole-amine is a metabolite of Mebendazole. Mebendazole is a broad-spectrum benzimidazole anti-helminthic agent.
    Mebendazole-amine (Standard)
  • HY-A0154R
    Deslanoside (Standard)
    Deslanoside (Standard) is the analytical standard of Deslanoside. This product is intended for research and analytical applications. Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation. Deslanoside inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations .
    Deslanoside (Standard)
  • HY-W717548
    Safinamide acid
    Safinamide acid (Compound Imp-E) is the metabolite of Safinamide (HY-70057). Safinamide acid can be formed by hydrolysis of Safinamide intermediate under alkaline or acidic conditions. Safinamide acid is utilized to monitor process-related impurities and degradation products in safinamide samples.
    Safinamide acid
  • HY-126194
    Tolcapone 3-β-D-glucuronide
    Tolcapone 3-β-D-glucuronide (Ro 61-1448) is an O-methyl metabolite and the glucuronide metabolite of Tolcapone (Ro 40-7592; HY-17406). Tolcapone 3-β-D-glucuronide is pharmacologically inactive.
    Tolcapone 3-β-D-glucuronide
  • HY-W014993S1
    1,3-Dimethyluric acid-dsub>3
    1,3-Dimethyluric acid-d3 is deuterated labeled 1,3-Dimethyluric acid (HY-W014993). 1,3-Dimethyluric acid is a product of theophylline metabolism in man. 1,3-Dimethyluric acid is one of the purine components in urinary calculi.
    1,3-Dimethyluric acid-dsub>3</sub>
  • HY-137772R
    Captopril EP Impurity E (Standard)
    Captopril EP Impurity E (Standard) is the analytical standard of Captopril EP Impurity E. This product is intended for research and analytical applications. Captopril EP Impurity E is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM).
    Captopril EP Impurity E (Standard)
  • HY-125594
    T-1095A
    T-1095A is an active metabolite of T-1095 (HY-106158) (an SGLT inhibitor).
    T-1095A
  • HY-N9484S
    Menthofuran-13C2
    Menthofuran-13C2 is 13C labeled Menthol (HY-N1369). Menthol is an analgesic and TRPM8 modulator. TRPM8 is a cold temperature sensing ion channel, and Menthol can regulate TRPM8 to exert analgesic and anti-irritation mechanisms. Menthol stimulates cold receptors and produces a cooling sensation by inhibiting Ca++ currents in neuronal cell membranes. Menthol also improves oral nicotine rejection in mice.
    Menthofuran-<sup>13</sup>C<sub>2</sub>
  • HY-32350R
    Ercalcitriol (Standard)
    Ercalcitriol (Standard) is the analytical standard of Ercalcitriol. This product is intended for research and analytical applications. Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2.
    Ercalcitriol (Standard)
  • HY-Y0469R
    1-Aminohydantoin hydrochloride (Standard)
    1-Aminohydantoin (hydrochloride) (Standard) is the analytical standard of 1-Aminohydantoin (hydrochloride). This product is intended for research and analytical applications. 1-Aminohydantoin hydrochloride is a major metabolite of nitrofurantoin in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat, milk et.al. 1-Aminohydantoin hydrochloride covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of AHD before detection.
    1-Aminohydantoin hydrochloride (Standard)
  • HY-138573
    N-Acetyl Adamantamine
    N-Acetyl Adamantamine (1-Acetamidoadamantane) is a major metabolite of Amantadine (HY-B0402)[1].
    N-Acetyl Adamantamine
  • HY-137768
    Captopril EP Impurity B
    Captopril EP Impurity B is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM).
    Captopril EP Impurity B
  • HY-W013886
    Captopril EP Impurity J
    Captopril EP Impurity J is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM).
    Captopril EP Impurity J
  • HY-158623
    (±)13(14)-DiHDPA
    (±)13(14)-DiHDPA ((±)13,14-DiHDPE) a metabolite of Docosahexaenoic acid (DHA; HY-B2167) by P450 (CYP) metabolic pathways.
    (±)13(14)-DiHDPA
  • HY-G0011S
    Netupitant N-oxide-d6
    Netupitant N-oxide-d6 is the deuterium labeled Netupitant N-oxide, which is a metabolite of Netupitant.
    Netupitant N-oxide-d<sub>6</sub>
  • HY-W587489
    RL-603
    RL-603 is the metabolite of Anagrelide (HY-B0523). RL-603 exhibits platelet-lowering activity in mouse model.
    RL-603
  • HY-131270R
    Febuxostat impurity 8 (Standard)
    Febuxostat impurity 8 (Standard) is the analytical standard of Febuxostat impurity 8. This product is intended for research and analytical applications. Febuxostat impurity 8 is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM.
    Febuxostat impurity 8 (Standard)
  • HY-137769
    Captopril EP Impurity C
    Captopril EP Impurity C is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM).
    Captopril EP Impurity C
  • HY-133672
    (Rac)-Mono(3,5,5-trimethylhexyl) phthalate
    (Rac)-Mono(3,5,5-trimethylhexyl) phthalate is a important metabolite of commonly used phthalate plasticizers. (Rac)-Mono(3,5,5-trimethylhexyl) phthalate has immuno-suppressive effect.
    (Rac)-Mono(3,5,5-trimethylhexyl) phthalate
Cat. No. Product Name / Synonyms Application Reactivity